Celebrex - Arthritis Pain Relief
CELEBREX
Celecoxib
Celebrex, the medication designed to relieve the pain,
inflammation, and stiffness of Arthritis. Both osteoarthritis and adult
rheumatoid arthritis. By reducing pain, inflammation, and stiffness,
Celebrex can help people do everyday functions such as walking and
bending.
How does Celebrex work?
This medicine contains the active ingredient celecoxib,
which is a type of medicine known as a non-steroidal anti-inflammatory
drug (NSAID).
NSAIDs work by blocking the action of a substance in the body called
cyclo-oxygenase. Cyclo-oxygenase is involved in producing prostaglandins,
in response to injury or certain diseases. These prostaglandins cause
pain, swelling and inflammation. Because NSAIDs block the production of
these prostaglandins, they are effective at relieving pain and
inflammation.
Cyclo-oxygenase does not only produce prostaglandins that cause
inflammation. It also produces prostaglandins that have useful roles in
the body. There are two different forms of cyclo-oxygenase, COX-1 and
COX-2. COX-2 is the form that (among other things) produces prostaglandins
that cause inflammation. COX-1 does not produce inflammatory
prostaglandins, but does produce others that have useful effects,
including some that are involved in maintaining a healthy stomach and
intestinal lining.
Traditional NSAIDs, such as ibuprofen or diclofenac, block the action of
both COX-1 and COX-2, and this is why they can sometimes cause side
effects such as stomach irritation and peptic ulcers. Celecoxib belongs to
a new generation of NSAIDs that selectively block the action of COX-2.
This means that it stops the production of inflammatory prostaglandins,
without stopping the production of prostaglandins that protect the stomach
and intestines. It therefore reduces pain and inflammation, but is less
likely than traditional NSAIDs to cause side effects on the stomach and
intestines (although such side effects are still possible).
Read more about Celebrex
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