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Celexa, Seropram Information How Celexa, Seropram Works How SSRIs Work Although the brain chemistry of depression is not fully understood, there does exist a growing body of evidence to support the view that people with depression have an imbalance of the brains neurotransmitters. These are chemicals in the brain that allow nerve cells to communicate. One of these neurotransmitters is serotonin. An imbalance in serotonin may be an important factor in the development and severity of depression. SSRIs affect how much serotonin is available by blocking its reabsorption during transmission from one nerve cell in the brain to another. Serotonin is released from one nerve cell and passed to the next. In the process, some of the serotonin released is reabsorbed by the first nerve cell. SSRIs block the reabsorption of serotonin into the first nerve cell. It is this blocking action that causes an increased amount of serotonin to become available at the next nerve cell. This is how SSRIs affect the balance of serotonin in the brain. Back to Celexa, Seropram orderpage.
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